Biblio

Pooling together samples and testing the resulting mixture is gaining considerable interest as a potential method to markedly increase the rate of testing for SARS-CoV-2, given the resource limited conditions. Such pooling can also be employed for carrying out large scale diagnostic testing of other infectious diseases, especially when the available resources are limited. Therefore, it has become important to design a user-friendly tool to assist clinicians and policy makers, to determine optimal testing pool and sub-pool sizes for their specific scenarios. We have developed such a tool; the calculator web application is available at https://riteshsingh.github.io/poolsize/. The algorithms employed are described and analyzed in this paper, and their application to other scientific fields is also discussed. We find that pooling always reduces the expected number of tests in all the conditions, at the cost of test sensitivity. The No sub-pooling optimal pool size calculator will be the most widely applicable one, because limitations of sample quantity will restrict sub-pooling in most conditions.

Recommender system helps people in decision making by asking their preferences about various items and recommends other items that have not been rated yet and are similar to their taste. A traditional recommendation system aims at generating a set of recommendations based on inter-user similarity that will satisfy the target user. Positive preferences as well as negative preferences of the users are taken into account so as to find strongly related users. Weighted entropy is usedz as a similarity measure to determine the similar taste users. The target user is asked to fill in the ratings so as to identify the closely related users from the knowledge base and top N recommendations are produced accordingly. Results show a considerable amount of improvement in accuracy after using weighted entropy and opposite preferences as a similarity measure.

Formal techniques provide exhaustive design verification, but computational margins have an important negative impact on its efficiency. Sequential equivalence checking is an effective approach, but traditionally it has been only applied between circuit descriptions with one-to-one correspondence for states. Applying it between RTL descriptions and high-level reference models requires removing signals, variables and states exclusive of the RTL description so as to comply with the state correspondence restriction. In this paper, we extend a previous formal methodology for RTL verification with high-level models, to check also the signals and protocol implemented in the RTL design. This protocol implementation is compared formally to a description captured from the specification. Thus, we can prove thoroughly the sequential behavior of a design under verification.