Biblio

Malware technology makes it difficult for malware analyst to detect same malware files with different obfuscation technique. In this paper we are trying to tackle that problem by analyzing the sequence of system call from an executable file. Malware files which actually are the same should have almost identical or at least a similar sequence of system calls. In this paper, we are going to create a model for each malware class consists of malwares from different families based on its sequence of system calls. Method/algorithm that's used in this paper is profile hidden markov model which is a very well-known tool in the biological informatics field for comparing DNA and protein sequences. Malware classes that we are going to build are trojan and worm class. Accuracy for these classes are pretty high, it's above 90% with also a high false positive rate around 37%.

Genes, proteins and other metabolites present in cellular environment exhibit a virtual network that represents the regulatory relationship among its constituents. This network is called Gene Regulatory Network (GRN). Computational reconstruction of GRN reveals the normal metabolic pathway as well as disease motifs. Availability of microarray gene expression data from normal and diseased tissues makes the job easier for computational biologists. Reconstruction of GRN is based on neural modeling. Here we have used discrete and continuous versions of a meta-heuristic algorithm named Firefly algorithm for structure and parameter learning of GRNs respectively. The discrete version for this problem is proposed by us and it has been applied to explore the discrete search space of GRN structure. To evaluate performance of the algorithm, we have used a widely used synthetic GRN data set. The algorithm shows an accuracy rate above 50% in finding GRN. The accuracy level of the performance of Firefly algorithm in structure and parameter optimization of GRN is promising.