Biblio

Access to data at large scales expedites the progress of research in medical fields. Nevertheless, accessibility to patients' data faces significant challenges on regulatory, organizational and technical levels. In light of this, we present a novel approach based on the crowdsourcing paradigm to solve this data scarcity problem. Utilizing the infrastructure that blockchain provides, our decentralized platform enables researchers to solicit contributions to their well-defined research study from a large crowd of volunteers. Furthermore, to overcome the challenge of breach of privacy and mutual trust, we employed the cryptographic primitive of Zero-knowledge Argument of Knowledge (zk-SNARK). This not only allows participants to make contributions without exposing their privacy-sensitive health data, but also provides a means for a distributed network of users to verify the validity of the contributions in an efficient manner. Finally, since without an incentive mechanism in place, the crowdsourcing platform would be rendered ineffective, we incorporated smart contracts to ensure a fair reciprocal exchange of data for reward between patients and researchers.

We present a novel, and use case agnostic method of identifying and circumventing private data exposure across distributed and high-dimensional data repositories. Examples of distributed high-dimensional data repositories include medical research and treatment data, where oftentimes more than 300 describing attributes appear. As such, providing strong guarantees of data anonymity in these repositories is a hard constraint in adhering to privacy legislation. Yet, when applied to distributed high-dimensional data, existing anonymisation algorithms incur high levels of information loss and do not guarantee privacy defeating the purpose of anonymisation. In this paper, we address this issue by using Bayesian networks to handle data transformation for anonymisation. By evaluating every attribute combination to determine the privacy exposure risk, the conditional probability linking attribute pairs is computed. Pairs with a high conditional probability expose the risk of deanonymisation similar to quasi-identifiers and can be separated instead of deleted, as in previous algorithms. Attribute separation removes the risk of privacy exposure, and deletion avoidance results in a significant reduction in information loss. In other words, assimilating the conditional probability of outliers directly in the adjacency matrix in a greedy fashion is quick and thwarts de-anonymisation. Since identifying every privacy violating attribute combination is a W[2]-complete problem, we optimise the procedure with a multigrid solver method by evaluating the conditional probabilities between attribute pairs, and aggregating state space explosion of attribute pairs through manifold learning. Finally, incremental processing of new data is achieved through inexpensive, continuous (delta) learning.