Biblio

This study develops a framework for personalized care to tackle heart disease risk using an at-home system. The machine learning models used to predict heart disease are Logistic Regression, K - Nearest Neighbor, Support Vector Machine, Naive Bayes, Decision Tree, Random Forest and XG Boost. Timely and efficient detection of heart disease plays an important role in health care. It is essential to detect cardiovascular disease (CVD) at the earliest, consult a specialist doctor before the severity of the disease and start medication. The performance of the proposed model was assessed using the Cleveland Heart Disease dataset from the UCI Machine Learning Repository. Compared to all machine learning algorithms, the Random Forest algorithm shows a better performance accuracy score of 90.16%. The best model may evaluate patient fitness rather than routine hospital visits. The proposed work will reduce the burden on hospitals and help hospitals reach only critical patients.

Healthcare has become one of the most important aspects of people’s lives, resulting in a surge in medical big data. Healthcare providers are increasingly using Internet of Things (IoT)-based wearable technologies to speed up diagnosis and treatment. In recent years, Through the Internet, billions of sensors, gadgets, and vehicles have been connected. One such example is for the treatment and care of patients, technology—remote patient monitoring—is already commonplace. However, these technologies also offer serious privacy and data security problems. Data transactions are transferred and logged. These medical data security and privacy issues might ensue from a pause in therapy, putting the patient’s life in jeopardy. We planned a framework to manage and analyse healthcare large data in a safe manner based on blockchain. Our model’s enhanced privacy and security characteristics are based on data sanitization and restoration techniques. The framework shown here make data and transactions more secure.

In recent years, business environments are undergoing disruptive changes across sectors [1]. Globalization and technological advances, such as artificial intelligence and the internet of things, have completely redesigned business activities, bringing to light an ever-increasing interest and attention towards the customer [2], especially in healthcare sector. In this context, researchers is paying more and more attention to the introduction of new technologies capable of meeting the patients’ needs [3, 4] and the Covid-19 pandemic has contributed and still contributes to accelerate this phenomenon [5]. Therefore, emerging technologies (i.e., AI-enabled solutions, service robots, conversational agents) are proving to be effective partners in improving medical care and quality of life [6]. Conversational agents, often identified in other ways as “chatbots”, are AI-enabled service robots based on the use of text [7] and capable of interpreting natural language and ensuring automation of responses by emulating human behavior [8, 9, 10]. Their introduction is linked to help institutions and doctors in the management of their patients [11, 12], at the same time maintaining the negligible incremental costs thanks to their virtual aspect [13–14]. However, while the utilization of these tools has significantly increased during the pandemic [15, 16, 17], it is unclear what benefits they bring to service delivery. In order to identify their contributions, there is a need to find out which activities can be supported by conversational agents.This paper takes a grounded approach [18] to achieve contextual understanding design and to effectively interpret the context and meanings related to conversational agents in healthcare interactions. The study context concerns six chatbots adopted in the healthcare sector through semi-structured interviews conducted in the health ecosystem. Secondary data relating to these tools under consideration are also used to complete the picture on them. Observation, interviewing and archival documents [19] could be used in qualitative research to make comparisons and obtain enriched results due to the opportunity to bridge the weaknesses of one source by compensating it with the strengths of others. Conversational agents automate customer interactions with smart meaningful interactions powered by Artificial Intelligence, making support, information provision and contextual understanding scalable. They help doctors to conduct the conversations that matter with their patients. In this context, conversational agents play a critical role in making relevant healthcare information accessible to the right stakeholders at the right time, defining an ever-present accessible solution for patients’ needs. In summary, conversational agents cannot replace the role of doctors but help them to manage patients. By conveying constant presence and fast information, they help doctors to build close relationships and trust with patients.

While 5G Edge Computing along with IoT technology has transformed the future of healthcare data transmission, it presents security vulnerabilities and risks when transmitting patients' confidential information. Currently, there are very few reliable security solutions available for healthcare data that routes through SDN routers in 5G Edge Computing. These solutions do not provide cryptographic security from IoT sensor devices. In this paper, we studied how 5G edge computing integrated with IoT network helps healthcare data transmission for remote medical treatment, explored security risks associated with unsecured data transmission, and finally proposed a cryptographic end-to-end security solution initiated at IoT sensor devices and routed through SDN routers. Our proposed solution with cryptographic security initiated at IoT sensor goes through SDN control plane and data plane in 5G edge computing and provides an end-to-end secured communication from IoT device to doctor's office. A prototype built with two-layer encrypted communication has been lab tested with promising results. This analysis will help future security implementation for eHealth in 5G and beyond networks.

Cybersecurity has become an emerging challenge for business information management and critical infrastructure protection in recent years. Artificial Intelligence (AI) has been widely used in different fields, but it is still relatively new in the area of Cyber-Physical Systems (CPS) security. In this paper, we provide an approach based on Machine Learning (ML) to intelligent threat recognition to enable run-time risk assessment for superior situation awareness in CPS security monitoring. With the aim of classifying malicious activity, several machine learning methods, such as k-nearest neighbours (kNN), Naïve Bayes (NB), Support Vector Machine (SVM), Decision Tree (DT) and Random Forest (RF), have been applied and compared using two different publicly available real-world testbeds. The results show that RF allowed for the best classification performance. When used in reference industrial applications, the approach allows security control room operators to get notified of threats only when classification confidence will be above a threshold, hence reducing the stress of security managers and effectively supporting their decisions.

IT world is migrating towards utilizing cloud computing as an essential data storing and exchanging platform. With the amelioration of technology, a colossal amount of data is generating with time. Cloud computing provides an enormous data storage capacity with the flexibility of accessing it without the time and place restrictions with virtualized resources. Healthcare industries spawn intense amounts of data from various medical instruments and digital records of patients. To access data remotely from any geographical location, the healthcare industry is moving towards cloud computing. EHR and PHR are patient's digital records, which include sensitive information of patients. Apart from all the proficient service provided by cloud computing, security is a primary concern for various organizations. To address the security issue, several cryptographic techniques implemented by researchers worldwide. In this paper, a vigorous cryptographic method discussed which is implemented by combining DNA cryptography and Elliptic Curve Cryptography to protect sensitive data in the cloud.

The paper deals with exponentially growing technology - Internet of Things (IoT) in the field of healthcare. It is spoken about the networked healthcare and medical architecture. The attention is given to the analysis of the international regulations on medical and healthcare cybersecurity. For building a trustworthy healthcare IoT solution, a developed normative hierarchical model of the international cybersecurity standards is provided. For cybersecurity assessment of such systems the case-oriented technique, which includes Advanced Security Assurance Case (ASAC) and an example on a wireless insulin pump of its application are provided.

Over the last few years, the world has been moving towards digital healthcare, where harnessing medical data distributed across multiple healthcare providers is essential to achieving personalized treatments. Though the efficiency and speed of the diagnosis process have increased due to the digitalization of healthcare data, it is at constant risk of cyberattacks. Medical images, in particular, seem to have become a regular victim of hackers, due to which there is a need to find a feasible solution for storing them securely. This work proposes a blockchain-based framework that leverages the InterPlanetary File system (IPFS) to provide decentralized storage for medical images. Our proposed blockchain storage model is implemented in the IPFS distributed file-sharing system, where each image is stored on IPFS, and its corresponding unique content-addressed hash is stored in the blockchain. The proposed model ensures the security of the medical images without any third-party dependency and eliminates the obstacles that arise due to centralized storage.

The recent analysis indicates more than 250,000 people in the United States of America (USA) die every year because of medical errors. World Health Organisation (WHO) reports states that 2.6 million deaths occur due to medical and its prescription errors. Many of the errors related to the wrong drug/dosage administration by caregivers to patients due to indecipherable handwritings, drug interactions, confusing drug names, etc. The espousal of Mobile-based speech recognition applications will eliminate the errors. This allows physicians to narrate the prescription instead of writing. The application can be accessed through smartphones and can be used easily by everyone. An application program interface has been created for handling requests. Natural language processing is used to read text, interpret and determine the important words for generating prescriptions. The patient data is stored and used according to the Health Insurance Portability and Accountability Act of 1996 (HIPAA) guidelines. The SMS4-BSK encryption scheme is used to provide the data transmission securely over Wireless LAN.

mHealth apps have a vital role in facilitation of human health management. Users have to enter sensitive health related information in these apps to fully utilize their functionality. Unauthorized sharing of sensitive health information is undesirable by the users. mHealth apps also collect data other than that required for their functionality like surfing behavior of a user or hardware details of devices used. mHealth software and their developers also share such data with third parties for reasons other than medical support provision to the user, like advertisements of medicine and health insurance plans. Existence of a comprehensive and easy to understand data privacy policy, on user data acquisition, sharing and management is a salient requirement of modern user privacy protection demands. Readability is one parameter by which ease of understanding of privacy policy is determined. In this research, privacy policies of 27 free Android, medical apps are analyzed. Apps having user rating of 4.0 and downloads of 1 Million or more are included in data set of this research.RGL, Flesch-Kincaid Reading Grade Level, SMOG, Gunning Fox, Word Count, and Flesch Reading Ease of privacy policies are calculated. Average Reading Grade Level of privacy policies is 8.5. It is slightly greater than average adult RGL in the US. Free mHealth apps have a large number of users in other, less educated parts of the World. Privacy policies with an average RGL of 8.5 may be difficult to comprehend in less educated populations.

In today's smart healthcare system, medical records of patients are exposed to a large number of users for various purposes, from monitoring the patients' health to data analysis. Preserving the privacy of a patient has become an important and challenging issue. outsourced Ciphertext-Policy Attribute-Based Encryption (CP-ABE) provides a solution for the data sharing and privacy preservation problem in the healthcare system in fog environment. However, the high computational cost in case of frequent attribute updates renders it infeasible for providing access control in healthcare systems. In this paper, we propose an efficient method to overcome the frequent attribute update problem of outsourced CP-ABE. In our proposed approach, we generate two keys for each user (a static key and a dynamic key) based on the constant and changing attributes of the users. Therefore, in case of an attribute change for a user, only the dynamic key is updated. Also, the key update is done at the fog nodes without compromising the security of the system. Thus, both the communication and the computational overhead associated with the key update in the outsourced CP-ABE scheme are reduced, making it an ideal solution for data access control in healthcare systems. The efficacy of our proposed approach is shown through theoretical analysis and experimentation.

This research provides security and safety extensions to a blockchain based solution whose target is e-health. The Advanced Blockchain platform is extended with intelligent monitoring for security and machine learning for detecting patient treatment medication safety issues. For the reasons of stringent HIPAA, HITECH, EU-GDPR and other regional regulations dictating security, safety and privacy requirements, the e-Health blockchains have to cover mandatory disclosure of violations or enforcements of policies during transaction flows involving healthcare. Our service solution further provides the benefits of resolving the abnormal flows of a medical treatment process, providing accountability of the service providers, enabling a trust health information environment for institutions to handle medication safely, giving patients a better safety guarantee, and enabling the authorities to supervise the security and safety of e-Health blockchains. The capabilities can be generalized to support a uniform smart solution across industry in a variety of blockchain applications.

In recent years, there is fast growth in the high throughput DNA sequencing technology, and also there is a reduction in the cost of genome-sequencing, that has led to a advances in the genetic industries. However, the reduction in cost and time required for DNA sequencing there is still an issue of managing such large amount of data. Also, the security and transmission of such huge amount of DNA sequence data is still an issue. The idea is to provide a secure storage platform for future generation bioinformatics systems for both researchers and healthcare user. Secure data sharing strategies, that can permit the healthcare providers along with their secured substances for verifying the accuracy of data, are crucial for ensuring proper medical services. In this paper, it has been surveyed about the applications of blockchain technology for securing healthcare data, where the recorded information is encrypted so that it becomes difficult to penetrate or being removed, as the primary goals of block-chaining technology is to make data immutable.

Video streams acquired from thermal cameras are proven to be beneficial in diverse number of fields including military, healthcare, law enforcement, and security. Despite the hype, thermal imaging is increasingly affected by poor resolution, where it has expensive optical sensors and inability to attain optical precision. In recent years, deep learning based super-resolution algorithms are developed to enhance the video frame resolution at high accuracy. This paper presents a comparative analysis of super resolution (SR) techniques based on deep neural networks (DNN) that are applied on thermal video dataset. SRCNN, EDSR, Auto-encoder, and SRGAN are also discussed and investigated. Further the results on benchmark thermal datasets including FLIR, OSU thermal pedestrian database and OSU color thermal database are evaluated and analyzed. Based on the experimental results, it is concluded that, SRGAN has delivered a superior performance on thermal frames when compared to other techniques and improvements, which has the ability to provide state-of-the art performance in real time operations.

Latest forecasts show that 50 billion devices will be connected to the Internet by 2020. These devices will provide ubiquitous data access and enable smarter interactions in all aspects of our everyday life, including vital domains such as healthcare and battlefields, where privacy is a key requirement. With the increasing adoption of IoT and the explosion of these resource-constrained devices, manual discovery and configuration become significantly challenging. Despite there is a number of resource discovery protocols that can be efficiently used in IoT deployments, none of these protocols provides any privacy consideration. This paper presents LPA-SDT, a novel technique for service discovery that builds privacy into the design from the ground up. Performance evaluation demonstrates that LPA-SDT outperforms state-of-the-art discovery techniques for resource-constrained environments while preserving user and data privacy.

The e-government concept and healthcare have usually been studied separately. Even when and where both e-government and healthcare systems were combined in a study, the roles of e-government in healthcare have not been examined. As a result., the complementarity of the systems poses potential challenges. The interpretive approach was applied in this study. Existing materials in the areas of healthcare and e-government were used as data from a qualitative method viewpoint. Dimension of change from the perspective of the structuration theory was employed to guide the data analysis. From the analysis., six factors were found to be the main roles of e-government in the implementation and application of e-health in the delivering of healthcare services. An understanding of the roles of e-government promotes complementarity., which enhances the healthcare service delivery to the community.

Cyber Physical Systems (CPS)-Internet of Things (IoT) enabled healthcare services and infrastructures improve human life, but are vulnerable to a variety of emerging cyber-attacks. Cybersecurity specialists are finding it hard to keep pace of the increasingly sophisticated attack methods. There is a critical need for innovative cognitive cybersecurity for CPS-IoT enabled healthcare ecosystem. This paper presents a cognitive cybersecurity framework for simulating the human cognitive behaviour to anticipate and respond to new and emerging cybersecurity and privacy threats to CPS-IoT and critical infrastructure systems. It includes the conceptualisation and description of a layered architecture which combines Artificial Intelligence, cognitive methods and innovative security mechanisms.

The integration of Internet-of-Things and pervasive computing in medical devices have made the modern healthcare system “smart.” Today, the function of the healthcare system is not limited to treat the patients only. With the help of implantable medical devices and wearables, Smart Healthcare System (SHS) can continuously monitor different vital signs of a patient and automatically detect and prevent critical medical conditions. However, these increasing functionalities of SHS raise several security concerns and attackers can exploit the SHS in numerous ways: they can impede normal function of the SHS, inject false data to change vital signs, and tamper a medical device to change the outcome of a medical emergency. In this paper, we propose HealthGuard, a novel machine learning-based security framework to detect malicious activities in a SHS. HealthGuard observes the vital signs of different connected devices of a SHS and correlates the vitals to understand the changes in body functions of the patient to distinguish benign and malicious activities. HealthGuard utilizes four different machine learning-based detection techniques (Artificial Neural Network, Decision Tree, Random Forest, k-Nearest Neighbor) to detect malicious activities in a SHS. We trained HealthGuard with data collected for eight different smart medical devices for twelve benign events including seven normal user activities and five disease-affected events. Furthermore, we evaluated the performance of HealthGuard against three different malicious threats. Our extensive evaluation shows that HealthGuard is an effective security framework for SHS with an accuracy of 91 % and an F1 score of 90 %.

Medical Internet of Things (MIoT) offers innovative solutions to a healthier life, making radical changes in people's lives. Healthcare providers are enabled to continuously and remotely monitor their patients for many medial issues outside hospitals and healthcare providers' offices. MIoT systems and applications lead to increase availability, accessibility, quality and cost-effectiveness of healthcare services. On the other hand, MIoT devices generate a large amount of diverse real-time data, which is highly sensitive. Thus, securing medical data is an essential requirement when developing MIoT architectures. However, the MIoT architectures being developed in the literature have many security issues. To address the challenge of data security in MIoT, the integration of fog computing and MIoT is studied as an emerging and appropriate solution. By data security, it means that medial data is stored in fog nodes and transferred to the cloud in a secure manner to prevent any unauthorized access. In this paper, we propose a design for a secure fog-cloud based architecture for MIoT.

The healthcare sector is exploring the incorporation of digital solutions in order to improve access, reduce costs, increase quality and enhance their capacity in reaching a higher number of citizens. However, this opens healthcare organisations' systems to external elements used within or beyond their premises, new risks and vulnerabilities in what regards cyber threats and incidents. We propose the creation of a Security Assessment as a Service (SAaaS) crosslayered system that is able to identify vulnerabilities and proactively assess and mitigate threats in an IT healthcare ecosystem exposed to external devices and interfaces, considering that most users are not experts (even technologically illiterate") in cyber security and, thus, unaware of security tactics or policies whatsoever. The SAaaS can be integrated in an IT healthcare environment allowing the monitoring of existing and new devices, the limitation of connectivity and privileges to new devices, assess a device's cybersecurity risk and - based on the device's behaviour - the assignment and revoking of privileges. The SAaaS brings a controlled cyber aware environment that assures security, confidentiality and trust, even in the presence of non-trusted devices and environments.

Internet of Things (IoT) is a contemporary concept for connecting the existing things in our environment with the Internet for a sake of making the objects information are accessible from anywhere and anytime to support a modern life style based on the Internet. With the rapid development of the IoT technologies and widely spreading in most of the fields such as buildings, health, education, transportation and agriculture. Thus, the IoT applications require increasing data collection from the IoT devices to send these data to the applications or servers which collect or analyze the data, so it is a very important to secure the data and ensure that do not reach a malicious adversary. This paper reviews some attacks in the IoT applications and the security weaknesses in the IoT environment. In addition, this study presents the challenges of IoT in terms of hardware, network and software. Moreover, this paper summarizes and points to some attacks on the smart car, smart home, smart campus, smart farm and healthcare.

With the vision of building "A Smart World", Internet of Things (IoT) plays a crucial role where users, computing systems and objects with sensing and actuating capabilities cooperate with unparalleled convenience. Among many applications of IoT, healthcare is the most emerging in today's scenario, as new technological advancement creates opportunity for early detection of illnesses, quick decision generation and even aftercare monitoring. Nowadays, it has become a reality for many patients to be monitored remotely, overcoming traditional logistical obstacles. However, these e-health applications increase the concerns of security, privacy, and integrity of medical data. For secured transmission in IoT healthcare, data that has been gathered from sensors in a patient's body area network needs to be sent to the end user and might need to be aggregated, visualized and/or evaluated before being presented. Here, trust is critical. Therefore, an end-to-end trustworthy system architecture can guarantee the reliable transmission of a patient's data and confirms the success of IoT Healthcare application.

Machine learning is being used in a wide range of application domains to discover patterns in large datasets. Increasingly, the results of machine learning drive critical decisions in applications related to healthcare and biomedicine. Such health-related applications are often sensitive, and thus, any security breach would be catastrophic. Naturally, the integrity of the results computed by machine learning is of great importance. Recent research has shown that some machine-learning algorithms can be compromised by augmenting their training datasets with malicious data, leading to a new class of attacks called poisoning attacks. Hindrance of a diagnosis may have life-threatening consequences and could cause distrust. On the other hand, not only may a false diagnosis prompt users to distrust the machine-learning algorithm and even abandon the entire system but also such a false positive classification may cause patient distress. In this paper, we present a systematic, algorithm-independent approach for mounting poisoning attacks across a wide range of machine-learning algorithms and healthcare datasets. The proposed attack procedure generates input data, which, when added to the training set, can either cause the results of machine learning to have targeted errors (e.g., increase the likelihood of classification into a specific class), or simply introduce arbitrary errors (incorrect classification). These attacks may be applied to both fixed and evolving datasets. They can be applied even when only statistics of the training dataset are available or, in some cases, even without access to the training dataset, although at a lower efficacy. We establish the effectiveness of the proposed attacks using a suite of six machine-learning algorithms and five healthcare datasets. Finally, we present countermeasures against the proposed generic attacks that are based on tracking and detecting deviations in various accuracy metrics, and benchmark their effectiveness.

Wearable medical devices are playing more and more important roles in healthcare. Unlike the wired connection, the wireless connection between wearable devices and the remote servers are exceptionally vulnerable to malicious attacks, and poses threats to the safety and privacy of the patient health data. Therefore, wearable medical devices require the implementation of reliable measures to secure the wireless network communication. However, those devices usually have limited computational power that is not comparable with the desktop computer and thus, it is difficult to adopt the full-fledged security algorithm in software. In this study, we have developed an efficient authentication and encryption protocol for internetconnected wearable devices using the recognized standards of AES and SHA that can provide two-way authentication between wearable device and remote server and protection of patient privacy against various network threats. We have tested the feasibility of this protocol on the TI CC3200 Launchpad, an evaluation board of the CC3200, which is a Wi-Fi capable microcontroller designed for wearable devices and includes a hardware accelerated cryptography module for the implementation of the encryption algorithm. The microcontroller serves as the wearable device client and a Linux computer serves as the server. The embedded client software was written in ANSI C and the server software was written in Python.

Wearables, such as Fitbit, Apple Watch, and Microsoft Band, with their rich collection of sensors, facilitate the tracking of healthcare- and wellness-related metrics. However, the assessment of the physiological metrics collected by these devices could also be useful in identifying the user of the wearable, e.g., to detect unauthorized use or to correctly associate the data to a user if wearables are shared among multiple users. Further, researchers and healthcare providers often rely on these smart wearables to monitor research subjects and patients in their natural environments over extended periods of time. Here, it is important to associate the sensed data with the corresponding user and to detect if a device is being used by an unauthorized individual, to ensure study compliance. Existing one-time authentication approaches using credentials (e.g., passwords, certificates) or trait-based biometrics (e.g., face, fingerprints, iris, voice) might fail, since such credentials can easily be shared among users. In this paper, we present a continuous and reliable wearable-user authentication mechanism using coarse-grain minute-level physical activity (step counts) and physiological data (heart rate, calorie burn, and metabolic equivalent of task). From our analysis of 421 Fitbit users from a two-year long health study, we are able to statistically distinguish nearly 100% of the subject-pairs and to identify subjects with an average accuracy of 92.97%.