This project is focused on the fundamental research in establishing a foundational framework towards the development of an autonomous Cyber-Physical System (CPS) through distributed computation in a Networked Control Systems (NCS) paradigm. Specific attention is focused on an application where the computational, and communication challenges are unique due to the sheer dimensionality of the physical system. An example of such CPS is the smart power grid, which includes large-scale deployment of distributed and networked Phasor Measurement Units (PMUs) and wind energy resources.