Cyber-physical systems (CPSs) and the Internet of Things (IoT) are converging towards a hybrid platform that is becoming ubiquitous in all modern infrastructures. The massive deployment of CPS requires comprehensive, secure, and reliable communication. The integration of complex and heterogeneous systems makes enormous space for the adversaries to get into the network and inject malicious data. To obfuscate and mislead the attackers, we propose DDAF, a deception defense-based data acquisition framework for a hierarchical communication network of CPSs.