Biblio

Recent projects regarding the exploration of the functions of microbiomes within communities brought about a plethora of new data. That specific field of study is called Metagenomics and one of its more advancing approach is the application of network analysis. The paper introduces NAMData which is a web-application tool for the network analysis of microbiome data. The system handles the compositionality and sparsity nature of microbiome data by applying taxa filtration, normalization, and zero treatment. Furthermore, compositionally aware correlation estimators were used to compute for the correlation between taxa and the system divides the network into the positive and negative correlation network. NAMData aims to capitalize on the unique network features namely network visualization, centrality scores, and community detection. The system enables researchers to include network analysis in their analysis pipelines even without any knowledge of programming. Biological concepts can be integrated with the network findings gathered from the system to either support existing facts or form new insights.