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Filters: Keyword is genetic epidemiology  [Clear All Filters]
2019-11-11
Kunihiro, Noboru, Lu, Wen-jie, Nishide, Takashi, Sakuma, Jun.  2018.  Outsourced Private Function Evaluation with Privacy Policy Enforcement. 2018 17th IEEE International Conference On Trust, Security And Privacy In Computing And Communications/ 12th IEEE International Conference On Big Data Science And Engineering (TrustCom/BigDataSE). :412–423.
We propose a novel framework for outsourced private function evaluation with privacy policy enforcement (OPFE-PPE). Suppose an evaluator evaluates a function with private data contributed by a data contributor, and a client obtains the result of the evaluation. OPFE-PPE enables a data contributor to enforce two different kinds of privacy policies to the process of function evaluation: evaluator policy and client policy. An evaluator policy restricts entities that can conduct function evaluation with the data. A client policy restricts entities that can obtain the result of function evaluation. We demonstrate our construction with three applications: personalized medication, genetic epidemiology, and prediction by machine learning. Experimental results show that the overhead caused by enforcing the two privacy policies is less than 10% compared to function evaluation by homomorphic encryption without any privacy policy enforcement.
2018-01-16
Ugwuoke, C., Erkin, Z., Lagendijk, R. L..  2017.  Privacy-safe linkage analysis with homomorphic encryption. 2017 25th European Signal Processing Conference (EUSIPCO). :961–965.

Genetic data are important dataset utilised in genetic epidemiology to investigate biologically coded information within the human genome. Enormous research has been delved into in recent years in order to fully sequence and understand the genome. Personalised medicine, patient response to treatments and relationships between specific genes and certain characteristics such as phenotypes and diseases, are positive impacts of studying the genome, just to mention a few. The sensitivity, longevity and non-modifiable nature of genetic data make it even more interesting, consequently, the security and privacy for the storage and processing of genomic data beg for attention. A common activity carried out by geneticists is the association analysis between allele-allele, or even a genetic locus and a disease. We demonstrate the use of cryptographic techniques such as homomorphic encryption schemes and multiparty computations, how such analysis can be carried out in a privacy friendly manner. We compute a 3 × 3 contingency table, and then, genome analyses algorithms such as linkage disequilibrium (LD) measures, all on the encrypted domain. Our computation guarantees privacy of the genome data under our security settings, and provides up to 98.4% improvement, compared to an existing solution.