A new, emergent cybersecurity frontier is information manipulation, whereby adversaries may attempt to distort information to influence opinion, thought, or action. Information manipulation can take many shapes and forms, from blatant attacks such as search-poisoning, misinformation such as bogus on-line reviews, to subtle distortion such as personalized search and biased news. Left unchecked, information manipulation can harm our economy, culture, and democracy. Past research efforts have been ad-hoc and focused on specific kinds of information manipulation.