Biblio

Preserving medical data is of utmost importance to stake holders. There are not many laws in India about preservation, usability of patient records. When data is transmitted across the globe there are chances of data getting tampered intentionally or accidentally. Tampered data loses its authenticity for diagnostic purpose, research and various other reasons. This paper proposes an authenticity based ECDSA algorithm by signature verification to identify the tampering of medical image files and alerts by the rules of authenticity. The algorithm can be used by researchers, doctors or any other educated person in order to maintain the authenticity of the record. Presently it is applied on medical related image files like DICOM. However, it can support any other medical related image files and still preserve the authenticity.

The availability of commercial fully immersive virtual reality systems allows the proposal and development of new applications that offer novel ways to visualize and interact with multidimensional neuroimaging data. We propose a system for the visualization and interaction with Magnetic Resonance Imaging (MRI) scans in a fully immersive learning environment in virtual reality. The system extracts the different slices from a DICOM file and presents the slices in a 3D environment where the user can display and rotate the MRI scan, and select the clipping plane in all the possible orientations. The 3D environment includes two parts: 1) a cube that displays the MRI scan in 3D and 2) three panels that include the axial, sagittal, and coronal views, where it is possible to directly access a desired slice. In addition, the environment includes a representation of the brain where it is possible to access and browse directly through the slices with the controller. This application can be used both for educational purposes as an immersive learning tool, and by neuroscience researchers as a more convenient way to browse through an MRI scan to better analyze 3D data.

Advances in deep neural networks (DNNs) have shown tremendous promise in the medical domain. However, the deep learning tools that are helping the domain, can also be used against it. Given the prevalence of fraud in the healthcare domain, it is important to consider the adversarial use of DNNs in manipulating sensitive data that is crucial to patient healthcare. In this work, we present the design and implementation of a DNN-based image translation attack on biomedical imagery. More specifically, we propose Jekyll, a neural style transfer framework that takes as input a biomedical image of a patient and translates it to a new image that indicates an attacker-chosen disease condition. The potential for fraudulent claims based on such generated `fake' medical images is significant, and we demonstrate successful attacks on both X-rays and retinal fundus image modalities. We show that these attacks manage to mislead both medical professionals and algorithmic detection schemes. Lastly, we also investigate defensive measures based on machine learning to detect images generated by Jekyll.

The objective of the work is to provide security to the medical images by embedding medical data (EPR-Electronic Patient Record) along with the image to reduce the bandwidth during communication. Reversible watermarking and Digital Signature itself will provide high security. This application mainly used in tele-surgery (Medical Expert to Medical Expert Communication). Only the authorized medical experts can explore the patients' image because of Kerberos. The proposed work is mainly to restrict the unauthorized access to get the patients'data. So medical image authentication may be achieved without biometric recognition such as finger prints and eye stamps etc. The EPR itself contains the patients' entire history, so after the extraction process Medical expert can able to identify the patient and also the disease information. In future we can embed the EPR inside the medical image after it got encrypted to achieve more security. To increase the authentication, Medical Expert biometric information can be embedded inside the image in the future. Experiments were conducted using more than 500 (512 × 512) image archives in various modalities from the NIH (National Institute of Health) and Aycan sample digital images downloaded from the internet and tests are conducted. Almost in all images with greater than 15000 bits embedding size and got PSNR of 60.4 dB to 78.9 dB with low distortion in received image because of compression, not because of watermarking and average NPCR (Number of Pixels Change Rate) is 98.9 %.

Density information has been used as a property of sound to restore objects in a quantitative manner in ultrasound tomography based on backscatter theory. In the traditional method, the authors only study the distorted Born iterative method (DBIM) to create density images using Tikhonov regularization. The downside is that the image quality is still low, the resolution is low, the convergence rate is not high. In this paper, we study the DBIM method to create density images using compressive sampling technique. With compressive sampling technique, the probes will be randomly distributed on the measurement system (unlike the traditional method, the probes are evenly distributed on the measurement system). This approach uses the l1 regularization to restore images. The proposed method will give superior results in image recovery quality, spatial resolution. The limitation of this method is that the imaging time is longer than the one in the traditional method, but the less number of iterations is used in this method.

In this paper, new image encryption based on singular value decomposition (SVD), fractional discrete cosine transform (FrDCT) and the chaotic system is proposed for the security of medical image. Reliability, vitality, and efficacy of medical image encryption are strengthened by it. The proposed method discusses the benefits of FrDCT over fractional Fourier transform. The key sensitivity of the proposed algorithm for different medical images inspires us to make a platform for other researchers. Theoretical and statistical tests are carried out demonstrating the high-level security of the proposed algorithm.

Tele-radiology is a technology that helps in bringing the communication between the radiologist, patients and healthcare units situated at distant places. This involves exchange of medical centric data. The medical data may be stored as Electronic Health Records (EHR). These EHRs contain X-Rays, CT scans, MRI reports. Hundreds of scans across multiple radiology centers lead to medical big data (MBD). Healthcare Cloud can be used to handle MBD. Since lack of security to EHRs can cause havoc in medical IT, healthcare cloud must be secure. It should ensure secure sharing and storage of EHRs. This paper proposes the application of decoy technique to provide security to EHRs. The EHRs have the risk of internal attacks and external intrusion. This work addresses and handles internal attacks. It also involves study on honey-pots and intrusion detection techniques. Further it identifies the possibility of an intrusion and alerts the administrator. Also the details of intrusions are logged.

The purpose of this article is to present an algorithm which maximizes prediction accuracy under a linear regression model while preserving data privacy. This approach anonymizes the data such that the privacy of the original features is fully guaranteed, and the deterioration in predictive accuracy using the anonymized data is minimal. The proposed algorithm employs two stages: the first stage uses a probabilistic latent factor approach to anonymize the original features into a collection of lower dimensional latent factors, while the second stage uses an optimization algorithm to tune the anonymized data further, in a way which ensures a minimal loss in prediction accuracy under the predictive approach specified by the user. We demonstrate the advantages of our approach via numerical studies and apply our method to high-dimensional neuroimaging data where the goal is to predict the behavior of adolescents and teenagers based on functional magnetic resonance imaging (fMRI) measurements.

The purpose of this article is to present an algorithm which maximizes prediction accuracy under a linear regression model while preserving data privacy. This approach anonymizes the data such that the privacy of the original features is fully guaranteed, and the deterioration in predictive accuracy using the anonymized data is minimal. The proposed algorithm employs two stages: the first stage uses a probabilistic latent factor approach to anonymize the original features into a collection of lower dimensional latent factors, while the second stage uses an optimization algorithm to tune the anonymized data further, in a way which ensures a minimal loss in prediction accuracy under the predictive approach specified by the user. We demonstrate the advantages of our approach via numerical studies and apply our method to high-dimensional neuroimaging data where the goal is to predict the behavior of adolescents and teenagers based on functional magnetic resonance imaging (fMRI) measurements.

The transmission of medical image data in an open network environment is subject to privacy issues including patient privacy and data leakage. In the past, image encryption and information-hiding technology have been used to solve such security problems. But these methodologies, in general, suffered from difficulties in retrieving original images. We present in this paper an algorithm to protect key regions in medical images. First, coefficient of variation is used to locate the key regions, a.k.a. the lesion areas, of an image; other areas are then processed in blocks and analyzed for texture complexity. Next, our reversible data-hiding algorithm is used to embed the contents from the lesion areas into a high-texture area, and the Arnold transformation is performed to protect the original lesion information. In addition to this, we use the ciphertext of the basic information about the image and the decryption parameter to generate the Quick Response (QR) Code to replace the original key regions. Consequently, only authorized customers can obtain the encryption key to extract information from encrypted images. Experimental results show that our algorithm can not only restore the original image without information loss, but also safely transfer the medical image copyright and patient-sensitive information.

The recent success of brain-inspired deep neural networks (DNNs) in solving complex, high-level visual tasks has led to rising expectations for their potential to match the human visual system. However, DNNs exhibit idiosyncrasies that suggest their visual representation and processing might be substantially different from human vision. One limitation of DNNs is that they are vulnerable to adversarial examples, input images on which subtle, carefully designed noises are added to fool a machine classifier. The robustness of the human visual system against adversarial examples is potentially of great importance as it could uncover a key mechanistic feature that machine vision is yet to incorporate. In this study, we compare the visual representations of white- and black-box adversarial examples in DNNs and humans by leveraging functional magnetic resonance imaging (fMRI). We find a small but significant difference in representation patterns for different (i.e. white- versus black-box) types of adversarial examples for both humans and DNNs. However, human performance on categorical judgment is not degraded by noise regardless of the type unlike DNN. These results suggest that adversarial examples may be differentially represented in the human visual system, but unable to affect the perceptual experience.

Wireless Capsule Endoscopy (WCE) is a noninvasive device for detection of gastrointestinal problems especially small bowel diseases, such as polyps which causes gastrointestinal bleeding. The quality of WCE images is very important for diagnosis. In this paper, a new method is proposed to improve the quality of WCE images. In our proposed method for improving the quality of WCE images, Removing Noise and Contrast Enhancement (RNCE) algorithm is used. The algorithm have been implemented and tested on some real images. Quality metrics used for performance evaluation of the proposed method is Structural Similarity Index Measure (SSIM), Peak Signal-to-Noise Ratio (PSNR) and Edge Strength Similarity for Image (ESSIM). The results obtained from SSIM, PSNR and ESSIM indicate that the implemented RNCE method improve the quality of WCE images significantly.

Optical Coherence Tomography (OCT) has shown a great potential as a complementary imaging tool in the diagnosis of skin diseases. Speckle noise is the most prominent artifact present in OCT images and could limit the interpretation and detection capabilities. In this work we evaluate various denoising filters with high edge-preserving potential for the reduction of speckle noise in 256 dermatological OCT B-scans. Our results show that the Enhanced Sigma Filter and the Block Matching 3-D (BM3D) as 2D denoising filters and the Wavelet Multiframe algorithm considering adjacent B-scans achieved the best results in terms of the enhancement quality metrics used. Our results suggest that a combination of 2D filtering followed by a wavelet based compounding algorithm may significantly reduce speckle, increasing signal-to-noise and contrast-to-noise ratios, without the need of extra acquisitions of the same frame.

The ultrafast active cavitation imaging (UACI) based on plane wave can be implemented with high frame rate, in which adaptive beamforming technique was introduced to enhance resolutions and signal-to-noise ratio (SNR) of images. However, regular adaptive beamforming continuously updates the spatial filter for each sample point, which requires a huge amount of calculation, especially in the case of a high sampling rate, and, moreover, 3D imaging. In order to achieve UACI rapidly with satisfactory resolution and SNR, this paper proposed an adaptive beamforming on the basis of compressive sensing (CS), which can retain the quality of adaptive beamforming but reduce the calculating amount substantially. The results of simulations and experiments showed that comparing with regular adaptive beamforming, this new method successfully achieved about eightfold in time consuming.

This paper addresses the issue of magnetic resonance (MR) Image reconstruction at compressive sampling (or compressed sensing) paradigm followed by its segmentation. To improve image reconstruction problem at low measurement space, weighted linear prediction and random noise injection at unobserved space are done first, followed by spatial domain de-noising through adaptive recursive filtering. Reconstructed image, however, suffers from imprecise and/or missing edges, boundaries, lines, curvatures etc. and residual noise. Curvelet transform is purposely used for removal of noise and edge enhancement through hard thresholding and suppression of approximate sub-bands, respectively. Finally Genetic algorithms (GAs) based clustering is done for segmentation of sharpen MR Image using weighted contribution of variance and entropy values. Extensive simulation results are shown to highlight performance improvement of both image reconstruction and segmentation problems.

In this paper, we investigate the performance of multiple-input multiple-output aided coded interleave division multiple access (IDMA) system for secured medical image transmission through wireless communication. We realize the MIMO profile using four transmit antennas at the base station and three receive antennas at the mobile station. We achieve bandwidth efficiency using discrete wavelet transform (DWT). Further we implement Arnold's Cat Map (ACM) encryption algorithm for secured medical transmission. We consider celulas as medical image which is used to differentiate between normal cell and carcinogenic cell. In order to accommodate more users' image, we consider IDMA as accessing scheme. At the mobile station (MS), we employ non-linear minimum mean square error (MMSE) detection algorithm to alleviate the effects of unwanted multiple users image information and multi-stream interference (MSI) in the context of downlink transmission. In particular, we investigate the effects of three types of delay-spread distributions pertaining to Stanford university interim (SUI) channel models for encrypted image transmission of MIMO-IDMA system. From our computer simulation, we reveal that DWT based coded MIMO- IDMA system with ACM provides superior picture quality in the context of DL communication while offering higher spectral efficiency and security.