DNA Origami

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Visible to the public Geometric Self Propelled Articulated Micro-Scale Devices

Novel techniques in micro-fabrication are integrated with geometric-based motion planning techniques to dramatically change the fundamental capabilities in applications as diverse as noninvasive surgical procedures and nano-scale manufacturing. This integration is achieved through the development of a closed-loop process that informs mechanical design via geometric modeling, constructs prototype systems across different physical scales, and conducts experimental trials to validate results.

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Visible to the public The Molecular Programming Project: Molecular Programming Architectures, Abstractions, Algorithms, and Applications

Our Expeditions in Computing aimed to establish the foundations for molecular programming as a new discipline within computer science. The UCSF site has primarily focused on realizing demand-meeting applications of the DNA origami method, building new experimental methods and computer-aided design tools to aid in those efforts, and inspiring the next generation of young scientists to join our growing community and gain hands-on experience in the lab through an annual biomolecular design competition.