Lab-on-a-Chip

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Visible to the public CPS: Synergy: Collaborative Research: Cyber-physical digital microfluidics based on active matrix electrowetting technology

This project will design and implement a domain-specific language and compiler for microfluidic laboratory-on-a-chip (LoC) devices based on electrowetting-on-dielectric (EWoD) technology. The Lead PI's team has designed and implemented BioScript, a domain-specific programming language for programmable microfluidics. The BioScript syntax is programmer friendly, with the intention of being accessible to biologists and other researchers and practitioners in the life sciences.

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Visible to the public System Support for Generally Programmable Digital Microfluidic Biochip Devices

This project has introduced a programming language, compiler, and runtime environment that enables software to control a "cyber-physical" microfluidic device in which integrated sensors and video monitoring equipment form a closed feedback loop (a). The technical contributions of the project include the design and implementation of the language, and a detailed description of the algorithms built into the compiler to enable fast decision-making in real-time in response to sensory feedback (b).